1 post on Sorceress about tile grid.
When you fit an image to pixel art grid, tile size wins before palette. Pick 16, 24, 32, or 48 in True Pixel, prep a hard-alpha plate with BG Remover, quantize against PICO-8 or Endesga 32, and export nearest-neighbor so the game engine imports the sprite pixel-perfect on its tilemap.
